In vitro effect of hydroxyethyl starch 130/0.42 on canine platelet function
作者: Janine ClassenKatja N. AdamikKarin WeberStephanie RubenbauerKatrin Hartmann
作者单位: 1Clinic of Small Animal Medicine, Ludwig Maximilian University, Veterinaerstrasse 13, 80539 Munich, Germany. (Classen, Weber, Hartmann); Clinic of Small Animals, Department of Clinical Veterinary Medicine, Vetsuisse University Bern, Laenggassstrasse 128, 3012 Bern, Switzerland. (Adamik); Institute of Statistics, Ludwig Maximilian University, Veterinaerstrasse 13, 80539 Munich, Germany. (Rubenbauer)
刊名: American Journal of Veterinary Research, 2012, Vol.73 (12)
来源数据库: TEMP
DOI: 10.2460/ajvr.73.12.1908
原始语种摘要: Objective—To evaluate the effect of 6% hydroxyethyl starch (HES) solution, with a molecular weight of 130 kDa and a degree of substitution of 0.42, on canine platelet function in vitro.(#br)Samples—Blood samples from 31 healthy adult dogs.(#br)Procedures—Citrated blood was diluted with saline (0.9% NaCl) solution or HES 130/0.42 in ratios of 1:9 (ie, 1 part saline solution or HES 130/0.42 and 9 parts blood) and 1:3. Platelet plug formation time (closure time [Ct]) was measured with a platelet function analyzer and cartridges coated with collagen and ADP.(#br)Results—Median baseline Ct with citrated blood was 84.0 seconds (interquartile range, 74.5 to 99.5 seconds). Results obtained with 1:9 dilutions with saline solution and HES 130/0.42 were not significantly different from baseline...
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影响因子:1.348 (2012)

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关键词翻译
关键词翻译
  • solution 溶液
  • range 射程
  • seconds 计秒
  • saline 盐的
  • baseline 基线
  • dilution 稀度
  • greater 较大
  • significantly 较大地
  • respectively 分别
  • prolonging 延长