Temporal correlation between differentiation factor expression and microRNAs in Holstein bovine skeletal muscle
作者: S. MirettiM. G. VolpeE. MartignaniP. AccorneroM. Baratta
作者单位: 1Department of Veterinary Science , University of Torino , Largo P. Braccini 2 , 10095 Grugliasco , Italy
刊名: animal, 2016, Vol.11 (2), pp.227-235
来源数据库: Cambridge University Press Journal
DOI: 10.1017/S1751731116001488
原始语种摘要: Satellite cells are adult stem cells located between the basal lamina and sarcolemma of muscle fibers. Under physiological conditions, satellite cells are quiescent, but they maintain a strong proliferative potential and propensity to differentiate, which underlies their critical role in muscle preservation and growth. MicroRNAs (miRNAs) play essential roles during animal development as well as in stem cell self-renewal and differentiation regulation. MiRNA-1, miRNA-133a and miRNA-206 are closely related muscle-specific miRNAs, and are thus defined myomiRNAs. MyomiRNAs are integrated into myogenic regulatory networks. Their expression is under the transcriptional and post-transcriptional control of myogenic factors and, in turn, they exhibit widespread control of muscle gene expression....
全文获取路径: Cambridge U Press 
影响因子:1.648 (2012)

  • expression 表示
  • muscle 肌肉
  • bovine 牛的
  • myogenic 肌原性的
  • expressed 榨出的
  • several 各自
  • between 在中间
  • complementary 补的
  • demonstrated 探明的储量
  • available 可供应的