Engineering of a Pluronic F127 functionalized magnetite/graphene nanohybrid for chemophototherapy
作者: Yongyong LiJiaqiang LiuHaiqing DongGuangzhen LiuHaiqing Hu
作者单位: 1The Institute for Biomedical Engineering and Nano Science, Tongji University School of Medicine, Shanghai 200092, People’s Republic of China
2School of Polymer Science and Engineering, Qingdao University of Science and Technology, Qingdao 266042, People’s Republic of China
刊名: Nanotechnology, 2014, Vol.25 (6)
来源数据库: Institute of Physics Journal
DOI: 10.1088/0957-4484/25/6/065602
原始语种摘要: In this study, a multifunctional graphene based nanohybrid, termed as GN/Fe3O4/PF127, is engineered via a facile one-pot process consisting of simultaneous reduction of graphene oxide/Fe3O4 and subsequent assembly of Pluronic F127 (PF127) onto graphene nanosheets (GNs). The unique aromatic and planar structure of GNs allows the attachment of multiple functional components including MRI contrast agent (Fe3O4 nanoparticles) and an aromatic anticancer drug like doxorubicin (DOX), as well as PF127 coating which imparts physiological dispersivity and stability to the nanohybrid. The successful assembly process is revealed by TEM observation, size and FITR monitoring. In contrast with the primitive graphene or its oxide...
全文获取路径: IOP 
影响因子:3.842 (2012)

  • magnetite 磁铁矿
  • dispersivity 分散性
  • assembly 组装
  • resulting 引起的
  • microscopy 显微镜检查
  • platform 台地
  • loaded 加负荷的
  • cytotoxic 细胞毒素的
  • effect 效应
  • simultaneous 同时的