Functional enrichment analysis based on long noncoding RNA associations
作者: Kuo-Sheng HungChung-Chi HsiaoTun-Wen PaiChin-Hwa HuWen-Shyong TzouWen-Der WangYet-Ran Chen
来源数据库: SJBM BioMed 文献
DOI: 10.1186/s12918-018-0571-0
关键词: LNCRNADIFFERENTIAL EXPRESSIONGENE ONTOLOGY (GO)KEGGNEURON DEVELOPMENT
原始语种摘要: Differential gene expression analysis using RNA-seq data is a popular approach for discovering specific regulation mechanisms under certain environmental settings. Both gene ontology (GO) and KEGG pathway enrichment analysis are major processes for investigating gene groups that participate in common biological responses or possess related functions. However, traditional approaches based on differentially expressed genes only detect a few significant GO terms and pathways, which are frequently insufficient to explain all-inclusive gene regulation mechanisms. Transcriptomes of survivin (birc5) gene knock-down experimental and wild-type control zebrafish embryos were sequenced and assembled, and a differential expression (DE) gene list was obtained for traditional functional enrichment...
全文获取路径: BMC 
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影响因子:2.982 (2012)

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关键词翻译
关键词翻译
  • enrichment 富集
  • analysis 分析
  • based 基于
  • RNA ROYAL NEPAL AIRLINES CORP.