Innovation in the field of Healthcare will create new landmarks in this field. The Health related information in any country is confidential and is available in large amount. Effective Management of Health Data is important. E-Health exists in various forms. Mostly, the People living in Urban Areas having each sort of facility like Mobile Phone and good Internet Connectivity but then also they do not know about the free services provided by the Hospitals. There is less awareness about E-Health services in India. In this paper we had discussed about the E-Health Initiatives in Uttar Pradesh, the E-Health Models, its Architecture and its scope in urban areas of Varanasi, in detail and how it is essential for the atomisation of Health Management System (H.M.S.). There are different forms of... E-Health discussed in this paper like Automated Physician Order Entry, E- Prescribing, Decision Support System, M-Health and Health Informatics.