|作者：||Mirosława Krauze-Baranowska, Marian Wiwart|
11Department of Pharmacognosy, Medical University of Gdańsk, Gen. J. Hallera 107 str., 80-416 Gdańsk, Poland.
22Department of Plant Breeding and Seed Production, University of Warmia and Mazury, Łódzki Sq. 3, 10-724 Olsztyn, Poland
|刊名：||Zeitschrift für Naturforschung C, 2015, Vol.58 (1-2), pp.65-69|
|来源数据库：||De Gruyter Journal|
|关键词：||Biflavones; Isolation; Antifungal Activity;|
|原始语种摘要：||Bilobetin and 4‴-O-methylamentoflavone were isolated and identified in the needles of Taxus baccata, for the first time in this species. The antifungal activity of biflavones from T. baccata and Ginkgo biloba, namely amentoflavone, 7-O-methylamentoflavone, bilobetin, ginkgetin, sciadopitysin and 2,3-dihydrosciadopitysin towards the fungi Alternaria alternata, Fusarium culmorum, Cladosporium oxysporum was determined employing computer-aided image analysis couplet to a microscope. Bilobetin exhibited a significant antifungal activity with values of ED50 14, 11 and 17 μm respectively. This compound completely inhibited the growth of germinating tubes of Cladosporium oxysporum and Fusarium culmorum at a concentration 100 μm. Activity of ginkgetin and 7-O-methylamentoflavone towards... Alternaria alternata was stronger than that of bilobetin. Moreover, slight structural changes in the cell wall of Alternaria alternata exposed to ginkgetin at concentration of 200 μm were observed|