Poly(3-hydroxybutyrate): Promising biomaterial for bone tissue engineering
作者: Barbara DarišŽeljko Knez
作者单位: 1University of Maribor , Faculty of Medicine, Institute of Biomedical Sciences , Maribor , Slovenia
2 University of Maribor , Faculty of Chemistry and Chemical Engineering , Laboratory for Separation Processes , Maribor , Slovenia
刊名: Acta Pharmaceutica, 2020, Vol.70 (1), pp.1-15
来源数据库: De Gruyter Journal
DOI: 10.2478/acph-2020-0007
关键词: Poly(3-hydroxybutyrate)BiopolymersBone tissue engineeringOsteoblasts
原始语种摘要: Abstract Poly(3-hydroxybutyrate) is a natural polymer, produced by different bacteria, with good biocompatibility and biodegradability. Cardiovascular patches, scaffolds in tissue engineering and drug carriers are some of the possible biomedical applications of poly(3-hydroxybutyrate). In the past decade, many researchers examined the different physico-chemical modifications of poly(3-hydroxybutyrate) in order to improve its properties for use in the field of bone tissue engineering. Poly(3-hydroxybutyrate) composites with hydroxyapatite and bioglass are intensively tested with animal and human osteoblasts in vitro to provide information about their biocompatibility, biodegradability and osteoinductivity. Good bone regeneration was proven when poly(3-hydroxy-butyrate) patches were...
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  • biomaterial 生物材料
  • engineering 工程
  • tissue 组织
  • hydroxyapatite 羟磷灰石层析
  • poly 
  • bioactivity 生物活性
  • biomedical 生物医学
  • recent 近来的
  • their 他们的
  • information 报告