Interleukin-6 as a Prognostic Biomarker in Ruptured Intracranial Aneurysms.
作者: Hung-Wen KaoKwo-Whei LeeChen-Ling KuoChing-Shan HuangWan-Min TsengChin-San LiuChing-Po Lin
刊名: PLoS ONE, 2017, Vol.10 (7)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0132115
原始语种摘要: Interleukin-6 (IL-6), a proinflammatory cytokine, was found to surge in the cerebral spinal fluid after aneurysmal subarachnoid hemorrhage (SAH). We hypothesized that the plasma level of IL-6 could be an independent biomarker in predicting clinical outcome of patients with ruptured intracranial aneurysm.We prospectively included 53 consecutive patients treated with platinum coil embolization of the ruptured intracranial aneurysm. Plasma IL-6 levels were measured in the blood samples at the orifices of the aneurysms and from peripheral veins. The outcome measure was the modified Rankin Scale one month after SAH. Multiple logistic regression analyses were used to evaluate the associations between the plasma IL-6 levels and the neurological outcome.Significant risk factors for the poor...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • intracranial 颅内的
  • aneurysmal 动脉瘤的
  • outcome 效果
  • ruptured 穿孔的
  • vasospasm 血管痉挛
  • grade 品位
  • embolization 栓塞
  • marginally 在边上
  • SAH 萨那
  • GCS Gate Controlled Switch