Plasmid profile of ESBL producing Gram-negative bacteria and correlation with susceptibility to β-lactam drugs
作者: Sharma JyotiRay PallabSharma Meera
刊名: Indian Journal of Pathology and Microbiology, 2010, Vol.53 (1), pp.83
来源数据库: Directory of Open Access Journals
关键词: Antibiotic resistancebeta lactamasesplasmids
原始语种摘要: Background: Members of family Enterobacteriaceae can acquire resistance to extended spectrum beta lactams by a number of mechanisms; most important being the plasmid encoded extended spectrum beta lactamase (ESBL) and AmpC beta lactamase. This study has been designed to look for the presence of plasmids and their correlation with drug resistance. Methods: ESBL production was studied in different gram-negative bacteria and susceptibility testing of ESBL positive isolates was done for various beta lactams, cephalosporins and other commonly used drugs against them. Plasmid DNA isolation of all the ESBL positive strains was done by alkalilysis method. Finally the presence of plasmid was correlated with susceptibility to beta lactam drugs. Results: E. coli , K. pneumoniae , Enterobacter...
全文获取路径: DOAJ  (合作)
影响因子:0.676 (2012)

  • susceptibility 磁化率
  • bacteria 细菌
  • isolates 单离体
  • profile 纵断图
  • cephalosporins 头孢菌素类
  • correlation 对比
  • extended 扩展
  • plasmid 质粒
  • isolation 隔离
  • against 反对