MicroRNAs of Bombyx mori identified by Solexa sequencing
作者: Liu ShipingLi DongLi QibinZhao PingXiang ZhonghuaiXia Qingyou
刊名: BMC Genomics, 2010, Vol.11 (1), pp.148
来源数据库: Directory of Open Access Journals
原始语种摘要: Abstract Background MicroRNA (miRNA) and other small regulatory RNAs contribute to the modulation of a large number of cellular processes. We sequenced three small RNA libraries prepared from the whole body, and the anterior-middle and posterior silk glands of Bombyx mori , with a view to expanding the repertoire of silkworm miRNAs and exploring transcriptional differences in miRNAs between segments of the silk gland. Results With the aid of large-scale Solexa sequencing technology, we validated 257 unique miRNA genes, including 202 novel and 55 previously reported genes, corresponding to 324 loci in the silkworm genome. Over 30 known silkworm miRNAs were further corrected in their sequence constitutes and length. A number of reads originated from the loop regions of the precursors of two...
全文获取路径: DOAJ  (合作)
影响因子:4.397 (2012)

  • sequencing 排序
  • silkworm 
  • evolution 进化
  • expression 表示
  • biogenesis 生源说
  • repertoire 指令表
  • posterior 修]后面[端;验
  • small 小的
  • gland 
  • anterior 前面的