MicroRNAs show diverse and dynamic expression patterns in multiple tissues of Bombyx mori
作者: Liu ShipingGao SongZhang DanyuYin JiyunXiang ZhonghuaiXia Qingyou
刊名: BMC Genomics, 2010, Vol.11 (1), pp.85
来源数据库: Directory of Open Access Journals
原始语种摘要: Abstract Background MicroRNAs (miRNAs) repress target genes at the post-transcriptional level, and function in the development and cell-lineage pathways of host species. Tissue-specific expression of miRNAs is highly relevant to their physiological roles in the corresponding tissues. However, to date, few miRNAs have been spatially identified in the silkworm. Results We establish for the first time the spatial expression patterns of nearly 100 miRNAs in multiple normal tissues (organs) of Bombyx mori females and males using microarray and Northern-blotting analyses. In all, only 10 miRNAs were universally distributed (including bmo-let-7 and bmo-bantam), while the majority were expressed exclusively or preferentially in specific tissue types (e.g., bmo-miR-275 and bmo-miR-1)....
全文获取路径: DOAJ  (合作)
影响因子:4.397 (2012)

  • expression 表示
  • diverse 钢的
  • developmental 试验性的
  • exclusively 专用于
  • midgut 中肠
  • metamorphosis 变态
  • functional 功能的
  • silkworm 
  • organs 男生殖器
  • specific