Increase in apoptotic effect of Panax ginseng by microwave processing in human prostate cancer cells: in vitro and in vivo studies
作者: Jun Yeon ParkPilju ChoiHo-kyong KimKi Sung KangJungyeob Ham
作者单位: 1College of Korean Medicine, Gachon University, Seongnam, Korea
2KIST Gangneung Institute of Natural Products, Korea Institute of Science and Technology, Gangneung, Korea
3Richwood Pharmaceutical Co., LTD., Seoul, Korea
刊名: Journal of Ginseng Research, 2016, Vol.40 (1), pp.62-67
来源数据库: Directory of Open Access Journals
DOI: 10.1016/j.jgr.2015.04.007
关键词: AnticancerGinsenosideMicrowavePanax ginsengProstate cancer
原始语种摘要: Background: Ginseng, which is widely used in functional foods and as an herbal medicine, has been reported to reduce the proliferation of prostate cancer cells by mechanisms that are not yet fully understood.Methods: This study was designed to investigate the changes in ginsenoside content in ginseng after treatment with a microwave-irradiation thermal process and to verify the anticancer effects of the extracts. To confirm the anticancer effect of microwave-irradiated processed ginseng (MG), it was tested in three human prostate cancer cell lines (DU145, LNCaP, and PC-3 cells). Involvements of apoptosis and autophagy were assessed using Western blotting.Results: After microwave treatment, the content of ginsenosides Rg1, Re, Rb1, Rc, Rb2, and Rd in the extracts decreased, whereas the...
全文获取路径: DOAJ  (合作)
影响因子:2.259 (2012)

  • ginseng 人参
  • prostate 前列腺
  • effect 效应
  • extracts 摘记
  • cancer 癌症
  • microwave 微波
  • ginsenoside 人参皂甙
  • processing 加工
  • cells 麻风细胞
  • treated 加工的