Calibration test of PET scanners in a multi-centre clinical trial on breast cancer therapy monitoring using 18F-FLT.
作者: Francis BouchetLilli GeworskiBernd O KnoopLudovic FerrerAlina Barriolo-RiedingerCorinne MillardetMarjolaine FourcadeAntoine MartineauAnne Belly-PoinsignonFrancis DjoumessiKarine TenderoLaurent KerosFrederic MontoyaChristel MesleardAnne-Laure MartinFranck LacoeuilleOlivier Couturier
刊名: PLoS ONE, 2017, Vol.8 (3)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0058152
原始语种摘要: A multi-centre trial using PET requires the analysis of images acquired on different systems We designed a multi-centre trial to estimate the value of 18F-FLT-PET to predict response to neoadjuvant chemotherapy in patients with newly diagnosed breast cancer. A calibration check of each PET-CT and of its peripheral devices was performed to evaluate the reliability of the results.11 centres were investigated. Dose calibrators were assessed by repeated measurements of a 68Ge certified source. The differences between the clocks associated with the dose calibrators and inherent to the PET systems were registered. The calibration of PET-CT was assessed with an homogeneous cylindrical phantom by comparing the activities per unit of volume calculated from the dose calibrator measurements with...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • calibration 校准
  • PET PagE frame Table
  • centre 电话总机
  • multi 多种
  • trial 试验
  • difference 区别
  • breast 胸部
  • certified 持有证明书的
  • calibrator 校准器
  • reliability 可靠性