The reliability of DIVA test based on M2e peptide exceed those based on HA2 or NS1 peptides
作者: Simson TariganSumarningsihJ. Ignjatovic
作者单位: 1BBLitvet
2University of Melbourne
刊名: Jurnal Ilmu Ternak dan Veteriner, 2015, Vol.20 (2), pp.126-133
来源数据库: Directory of Open Access Journals
DOI: 10.14334/jitv.v20i2.1167
关键词: M2eNS1 ProteinHA2 PeptideDIVA TestH5N1
原始语种摘要: One of the most important disadvantage of vaccination against avian influenza is that it cannot protect vaccinated birds against infection. When vaccinated poultry are heavily exposed to the virus, prolonged, unrecognised, subclinical infection may persist on the farm. The condition can only be serologically monitored by a DIVA (differentiation of infected from vaccinated animals) test, whereas conventional diagnostic tests cannot be used. The DIVA tests based on an antibody response following virus replication is the most appropriate approach. For H5N1 influenza such antibodies includes those to the M2e and NS1 proteins and an epitope on the HA2 subunit (HA_488-516). The purpose of this study was to compare the magnitude of the antibody response in chickens vaccinated and infected with...
全文获取路径: DOAJ  (合作)

  • vaccinated 接种疫苗的
  • DIVA Digital Input-Voice Answerback
  • antibody 抗体
  • peptide 
  • vaccination 注射疫苗
  • influenza 列性感冒
  • those 
  • epitope 抗原决定部位
  • infected 被感染
  • based 基于