ODC1 promotes proliferation and mobility via the AKT/GSK3Β/Β-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma
作者: Ye ZZeng ZShen YYang QChen DChen ZShen S
刊名: OncoTargets and Therapy, 2019, Vol.Volume 12 , pp.4081-4092
来源数据库: Directory of Open Access Journals
关键词: HCCODC1AcidoticΒ-catenin.
原始语种摘要: Zi Ye,1 Zhirui Zeng,2,3 Yiyi Shen,4 Qiang Yang,1 Duidui Chen,1 Zubing Chen,1 Shiqiang Shen11Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, People’s Republic of China; 2Guizhou Provincial Key Laboratory of Pathogenesis & Drug Research on Common Chronic Diseases, Guiyang, Guizhou 550009, People’s Republic of China; 3Department of Physiology, School of Basic Medicine, Guizhou Medical University, Guiyang, Guizhou 550009, People’s Republic of China; 4Department of Liver-Biliary Surgery, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, 550009, People’s Republic of ChinaPurpose: Ornithine decarboxylase 1 (ODC1)–an oncogene involved in the biosynthesis of polyamines–is commonly upregulated and associated with poor prognosis in...
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影响因子:2.073 (2012)

  • 脱羧酶 制止的
  • acidotic 定酸量的
  • hepatocellular 肝细胞性的
  • carcinoma 癌症
  • proliferation 增生
  • pathway 轨道
  • unfavorable 不利
  • suppressing 制止的
  • decarboxylase 制止的
  • invasion 侵入
  • mimetic 模仿的