Evaluation of the safety of intracameral trypan blue injection on corneal tissue using oxidative stress parameters and apoptotic activity: an experimental study
作者: Ali AkalTurgay UlasTugba GoncuMehmet Fatih AdibelliSezen KocarslanMuhammet Emin GuldurMuslum GulerUfuk OzkanMehmet DusunurTuncer Demir
刊名: Arquivos Brasileiros de Oftalmologia, 2018, Vol.77 (6), pp.388-391
来源数据库: Directory of Open Access Journals
DOI: 10.5935/0004-2749.20140096
关键词: Azul tripano/administração & dosagemInjeções intraocularesCórneaEstresse oxidativoApoptoseAnimaisRatos
原始语种摘要: Purpose: The present experimental study aimed to investigate the effects of intracameral trypan blue (TB) on oxidative stress parameters and apoptosis in corneal tissue. Methods: Thirty rats were randomly assigned to three groups of 10 rats each: the sham group (Group 1); control group (Group 2); and treatment group (Group 3). The control group was administered 0.01 cc of balanced salt solution. The treatment group was administered 0.006 mg/0.01 cc of TB. The total antioxidant status (TAS) and total oxidant status (TOS) in corneal tissue and blood were measured and the oxidative stress index (OSI) was calculated. Finally, corneal tissue histopathology was evaluated using staining for caspase-3 and -8, and apoptotic activity was examined. Results: The TAS, TOS and OSI levels in the blood...
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影响因子:0.379 (2012)

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关键词翻译
关键词翻译
  • safety 安全
  • corneal 角膜的
  • control 控制
  • oxidative 氧化的
  • group 
  • parameters 参数
  • tissue 组织
  • activity 活度
  • total 总和
  • injection 贯入