The transcriptome of equine peripheral blood mononuclear cells.
作者: Alicja PacholewskaMichaela DrögemüllerJolanta Klukowska-RötzlerSimone LanzEman HamzaEmmanouil T DermitzakisEliane MartiVincent GerberTosso LeebVidhya Jagannathan
刊名: PLoS ONE, 2017, Vol.10 (3)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0122011
原始语种摘要: Complete transcriptomic data at high resolution are available only for a few model organisms with medical importance. The gene structures of non-model organisms are mostly computationally predicted based on comparative genomics with other species. As a result, more than half of the horse gene models are known only by projection. Experimental data supporting these gene models are scarce. Moreover, most of the annotated equine genes are single-transcript genes. Utilizing RNA sequencing (RNA-seq) the experimental validation of predicted transcriptomes has become accessible at reasonable costs. To improve the horse genome annotation we performed RNA-seq on 561 samples of peripheral blood mononuclear cells (PBMCs) derived from 85 Warmblood horses. The mapped sequencing reads were used to build...
全文获取路径: DOAJ  (合作)
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影响因子:3.73 (2012)

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关键词翻译
关键词翻译
  • equine 马的
  • sequencing 排序
  • known 己知
  • horse 夹石
  • homologous 同结构型的
  • coding 编码
  • annotated 带注释
  • available 可供应的
  • predicted 预先计算的
  • RNA ROYAL NEPAL AIRLINES CORP.