Genome-Wide Association Study Reveals the PLAG1 Gene for Knuckle, Biceps and Shank Weight in Simmental Beef Cattle.
作者: Yuxin SongLingyang XuYan ChenLupei ZhangHuijiang GaoBo ZhuHong NiuWengang ZhangJiangwei XiaXue GaoJunya Li
刊名: PLoS ONE, 2017, Vol.11 (12)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0168316
原始语种摘要: Carcass traits of beef cattle have been genetically improved to increase yield of high quality meat. Genome-wide association study (GWAS) is a powerful method to identify genetic variants associated with carcass traits. For the 770K genotyped SNPs from 1141 Chinese Simmental cattle, we used the compressed mixed linear model (CMLM) to perform a genome-wide association study for knuckle, biceps and shank of beef carcass traits. Seventeen significantly associated SNPs were found, which are located on BTA6, BTA14 and BTA15. Interestingly, one pleiotropic quantitative trait nucleotide (QTN), named BovineHD1400007259 (p < 10-8) within the well-known gene region PLAG1-CHCHD7 on BTA14, was found to govern variation of the knuckle, biceps and shank traits. The QTN accounted for 8.6% of phenotypic...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • nucleotide 核苷酸
  • BTA 深孔加工
  • cattle 
  • carcass 机座
  • biceps 二头肌
  • powerful 强大的
  • knuckle 转向节
  • genetic 遗传的
  • region 地域
  • association 联合