Dendritic cells based immunotherapy of patient with chondrosarcoma--case report.
作者: Anna DmoszyńskaAdam KłosBeata PiechnikKrzysztof GiannopoulosPaulina WdowiakMagdalena WasiakIwona HusSebastian RadejJacek TabarkiewiczJacek Rolinski
刊名: Folia Histochemica et Cytobiologica, 2008, Vol.46 (2), pp.165-170
来源数据库: Directory of Open Access Journals
DOI: 10.5603/4437
原始语种摘要: We present a case report of patient with intracranial chondrosarcoma and attempt to use vaccination of dendritic cells as the salvage therapy. To our knowledge, this is the first case report of DCs vaccination in the head and neck chondrosarcoma. Immunotherapy with allogeneic DCs stimulated with tumor cell lysates in this case was demonstrated to be feasible, safe and well tolerated. Unfortunately we did not observe any clinical or immune response during vaccination. CD4+ and CD8+ regulatory cells could be responsible for ineffectiveness of immunotherapy.
全文获取路径: DOAJ  (合作)
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影响因子:1.101 (2012)

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关键词翻译
关键词翻译
  • chondrosarcoma 软骨肉瘤
  • case report 个案报告
  • immunotherapy 免疫疗法
  • vaccination 注射疫苗
  • cells 麻风细胞
  • patient 有耐性的
  • dendritic 师状的
  • regulatory 控制的
  • immune 免疫的
  • demonstrated 探明的储量