Bioactive Profiles, Antioxidant Activities, Nitrite Scavenging Capacities and Protective Effects on H2O2-Injured PC12 Cells of Glycyrrhiza Glabra L. Leaf and Root Extracts
作者: Yi DongMouming ZhaoTiantian ZhaoMengying FengHuiping ChenMingzhu ZhuangLianzhu Lin
作者单位: 1ollege of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, China
2College of Light Industry and Food Sciences, South China University of Technology, Guangzhou 510640, China
3College of Light Industry and Food Sciences, South China University of Techno
刊名: Molecules, 2014, Vol.19 (7), pp.9101-9113
来源数据库: Directory of Open Access Journals
DOI: 10.3390/molecules19079101
关键词: Glycyrrhiza glabra L. leafNitrite scavenging capacityTyrosinase inhibitory activityPC12 cellsPinocembrinLiquiritin
原始语种摘要: This study compared the total flavonoid content of Glycyrrhiza glabra L. leaf and root extracts. Results suggested that the total flavonoid content in the leaf extract was obviously higher than that in the root extract. Pinocembrin, the main compound in the leaf extract after purification by column chromatography, showed good antioxidant activity and nitrite scavenging capacity, but moderate inhibitory effect on mushroom tyrosinase. Liquiritin was the main compound in root extract and possessed strong inhibitory effect on mushroom tyrosinase. Both compounds exhibited significant protection effect on H2O2-injured PC12 cells at a low concentration. These results indicate that Glycyrrhiza glabra L. leaf is potential as an important raw material for functional food.
全文获取路径: DOAJ  (合作)
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影响因子:2.428 (2012)

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关键词翻译
关键词翻译
  • Glycyrrhiza 甘草属
  • mushroom 蘑菇
  • inhibitory 禁止的
  • possessed 占有的
  • extract 提取
  • scavenging 扫气
  • tyrosinase 酪氨酸酶
  • effect 效应
  • flavonoid 黄酮类
  • capacity 电容量