Association of Cortactin, Fascin-1 and Epidermal Growth Factor Receptor (EGFR) Expression in Ovarian Carcinomas: Correlation with Clinicopathological Parameters
作者: Chih-kung LinHer-Young SuWen-Chiuan TsaiLai-Fa SheuJong-Shiaw Jin
作者单位: 1epartment of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
2Department of Gynecology & Obstetrics, Tri-Service General Hospital; National Defense Medical Center, Taipei, Taiwan
3Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
4Department of Pathology, Tri-Service General Hospital, National Defense Medical
刊名: Disease Markers, 2008, Vol.25 (1), pp.17-26
来源数据库: Directory of Open Access Journals
DOI: 10.1155/2008/284382
原始语种摘要: Cortactin, fascin-1 and EGFR are recognized as important factors in tumor progression. We tested the hypothesis that cortactin, fascin-1 and EGFR expression correlates with clinicopathological parameters of the four most common ovarian surface epithelial carcinomas – serous cystadenocarcinoma, mucinous cystadenocarcinoma, endometrioid adenocarcinoma, and clear cell carcinoma. Immunohistochemical analysis of cortactin, fascin-1 and EGFR was performed using tissue microarrays of 172 specimens comprising 69 serous cystadenocarcinomas, 44 mucinous cystadenocarcinomas, 45 endometrioid adenocarcinomas and 14 clear cell carcinomas. All ovarian carcinomas showed significant expression of cortactin, fascin-1 and EGFR in staining intensity, tumor percentages and immunostaining scores. In addition,...
全文获取路径: DOAJ  (合作)
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影响因子:2.14 (2012)

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关键词翻译
关键词翻译
  • serous 浆液的
  • mucinous 粘质的
  • ovarian 卵巢的
  • endometrioid 子宫内膜样的
  • Association 美国公共卫生协会
  • correlated 相关
  • survival 生存
  • adenocarcinoma 腺癌
  • epithelial 上皮的
  • prognosis 预报