Characterizing Thalamocortical Disturbances in Cervical Spondylotic Myelopathy: Revealed by Functional Connectivity under Two Slow Frequency Bands.
作者: Fuqing ZhouLin WuXiaojia LiuHonghan GongKeith Dip-Kei LukYong Hu
刊名: PLoS ONE, 2017, Vol.10 (6)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0125913
原始语种摘要: Recent advanced MRI studies on cervical spondylotic myelopathy (CSM) revealed alterations of sensorimotor cortex, but the disturbances of large-scale thalamocortical systems remains elusive. The purpose of this study was to characterizing the CSM-related thalamocortical disturbances, which were associated with spinal cord structural injury, and clinical measures.A total of 17 patients with degenerative CSM and well-matched control subjects participated. Thalamocortical disturbances were quantified using thalamus seed-based functional connectivity in two distinct low frequencies bands (slow-5 and slow-4), with different neural manifestations. The clinical measures were evaluated by Japanese Orthopaedic Association (JOA) score system and Neck Disability Index (NDI) questionnaires.Decreased...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • degenerative 退化的
  • myelopathy 脊髓病
  • sensorimotor 感觉运动的
  • cervical 颈的
  • somatosensory 躯体感觉
  • impairment 减损
  • cortex 皮层
  • thalami 丘脑
  • spinal 脊柱的
  • functional 功能的