Influence of treatment in multiple sclerosis dysability: an open, retrospective, non-randomized long-term analysis Influência do tratamento na incapacidade da esclerose múltipla: estudo aberto, retrospectivo e não randomizado em longo prazo
作者: Lineu Cesar WerneckPaulo José LorenzoniVitor A RadünzMarco A.T UtiumiCláudia Suemi Kamoi KayRosana Herminia Scola
刊名: Arquivos de Neuro-Psiquiatria, 2010, Vol.68 (4), pp.511-521
来源数据库: Directory of Open Access Journals
DOI: 10.1590/S0004-282X2010000400008
关键词: Esclerose múltiplaTerapêutica imunomoduladoraTerapêutica imunossupressivaEDSSIncapacidade na esclerose múltiplaTratamento da esclerose múltiplaMultiple sclerosisImmunomodulatory therapyImmunosuppressive therapyEDSSMultiple sclerosis disabilityMultiple sclerosis treatment
原始语种摘要: The efficacies of immunosuppressive (IMS) and immunomodulatory (IMM) drugs for multiple sclerosis (MS) have been reported in several studies. These agents can reduce relapse rates and lesions observed by magnetic resonance imaging studies. However, the effect of these medications in disability progression over 4 years is rarely examined. OBJECTIVE: To study the disabilities associated with MS patients after a long time period and to analyze the therapeutic influence of different types of treatments in patient disease progression. METHOD: This is an open, uncontrolled, non-randomized, retrospective study of the disease progression using the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Severity Score (MSSS) in 155 cases of MS, which were 76% female with a mean age of...
全文获取路径: DOAJ  (合作)
影响因子:0.827 (2012)

  • treatment 处理
  • retrospective 追溯
  • sclerosis 硬化
  • initial 开首字母
  • disability 回弹率
  • statistically 统计地
  • interferon 干扰素
  • BET 贝塞尔
  • progress 发展
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