Efficacy and safety of total glucosides of paeony combined with methotrexate and leflunomide for active rheumatoid arthritis: a meta-analysis
作者: Huang YWang HChen ZWang YQin KHuang YBa XLin WTu S
刊名: Drug Design, Development and Therapy, 2019, Vol.Volume 13 , pp.1969-1984
来源数据库: Directory of Open Access Journals
关键词: Total glucosides of paeonyMethotrexateLeflunomideRheumatoid arthritisMeta-analysis
原始语种摘要: Yao Huang, Hui Wang, Zhe Chen, Yu Wang, Kai Qin, Ying Huang, Xin Ba, Weiji Lin, Shenghao TuInstitute of Integrated Traditional Chinese and Western Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, People’s Republic of ChinaPurpose: Total glucosides of paeony (TGP) have been confirmed to reduce hepatotoxicity caused by methotrexate (MTX) and leflunomide (LEF) in rheumatoid arthritis (RA). Nevertheless, high-quality evidence-based meta-analysis data on the issue are unavailable. This study aimed to evaluate the efficacy and safety of this combination treatment for RA.Materials and methods: PubMed, EMBASE, Web of Science, Cochrane Library, ClinicalTrials, Chinese Biomedical Literature database, China National Knowledge...
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影响因子:3.486 (2012)

  • rheumatoid 患风湿病的
  • arthritis 关节炎
  • paeony 牡丹
  • methotrexate 氨甲喋呤
  • combined 组合
  • lipoprotein 脂蛋白
  • analysis 分析
  • cholesterol 胆甾醇
  • safety 安全
  • density 密度