Prognostic and predictive markers of response to treatment in patients with locally advanced unresectable and metastatic pancreatic adenocarcinoma treated with gemcitabine/nab-paclitaxel: Results of a retrospective analysis
作者: Ana Fernández MontesPaula González VillarroelManuel Valladares AyerbesJuan De la Cámara GómezGuillermo Quintero AldanaLidia Vázquez TuñasMercedes Salgado FernándezMónica Jorge Fernández
刊名: Journal of Cancer Research and Therapeutics, 2017, Vol.13 (2), pp.240-245
来源数据库: Directory of Open Access Journals
DOI: 10.4103/0973-1482.181181
关键词: GemcitabineLocally advanced unresectable pancreatic cancerMetastatic pancreatic adenocarcinomaNab-paclitaxelPredictive markers
原始语种摘要: Background: Recent studies support the use of gemcitabine and nab-paclitaxel in adults with locally advanced unresectable or metastatic pancreatic adenocarcinoma although insufficient data are available on prognostic and predictive markers of response to treatment.Objective: The objective of this study is to identify treatment response markers in patients with locally advanced unresectable or metastatic pancreatic adenocarcinoma.Materials and Methods: This is an observational, retrospective, and multicenter study. Sociodemographic, clinical, and therapeutic data were collected. Cox regression models were applied to determine associations.Results: In total, 39 patients were included; 23.1% presented locally advanced pancreatic cancer and 76.9% metastatic disease. They received a mean of 6...
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影响因子:0.761 (2012)

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关键词翻译
关键词翻译
  • adenocarcinoma 腺癌
  • pancreatic 胰的
  • unresectable 不可切除的
  • metastatic 新陈代谢的
  • markers 时标
  • advanced 先进的
  • predictive 预言
  • locally 局部地
  • retrospective 追溯
  • treated 加工的