Omentin-1 is decreased in maternal plasma, placenta and adipose tissue of women with pre-existing obesity.
作者: Gillian BarkerRatana LimHarry M GeorgiouMartha Lappas
刊名: PLoS ONE, 2018, Vol.7 (8)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0042943
原始语种摘要: The aim of this study was to determine (i) the effect of maternal obesity and gestational diabetes mellitus (GDM) on (i) the circulating levels of omentin-1 in cord and maternal plasma, and (ii) gene expression and release of omentin-1 from human placenta and adipose tissue. The effect of pregnancy on circulating omentin-1 levels was also determined.Omentin-1 levels were measured in maternal and cord plasma from obese and non-obese normal glucose tolerant women (NGT; n = 44) and women with GDM (n = 39) at the time of term elective Caesarean section. Placenta and adipose tissue expression and release of omentin-1 was measured from 22 NGT and 22 GDM women collected at the time of term elective Caesarean section. Omentin-1 levels were also measured in maternal plasma from 13 NGT women at 11...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • maternal 母的
  • placenta 胎盘
  • adipose 脂肪的
  • women 妇女
  • GDM Global Data Manager
  • plasma 深绿玉髓
  • tissue 组织
  • obesity 肥胖
  • fetal 胎的
  • ponderal 氟苯丙胺盐酸盐