Extraction of Antioxidant Components from Bidens pilosa Flowers and Their Uptake by Human Intestinal Caco-2 Cells
作者: Charng-Cherng ChyauChi-Huang ChangShiau-Huei HuangChiung-Chi PengWen-Chin Lee
刊名: Molecules, 2013, Vol.18 (2), pp.1582-1601
来源数据库: Directory of Open Access Journals
DOI: 10.3390/molecules18021582
关键词: Bidens pilosa L. var. radiataChemical compositionAntioxidantHuman intestinal Caco-2 cell lineUptakeHPLC-MS
原始语种摘要: Bidens pilosa L. var. radiata (BPR, Asteraceae) is a commonly used folk medicine for treating various disorders such as diabetes, inflammation and hypertension. Recent studies to determine its chemical composition have revealed three di-O-caffeoylquinic acids (DiCQAs) and three polyacetylene glucosides (PGAs) to be among the major bioactive markers. To obtain the major compounds of these two chemical classes, the ethyl acetate fraction (EM) obtained using liquid-liquid partition from the methanol extract resulted in a fraction with the highest total phenolic and total flavonoid contents and antioxidant activities in radical scavenging and ferric reducing power assays. To assess the bioavailability of EM, we examined the in vitro uptake using the Caco-2 human colonic cell line. The...
全文获取路径: DOAJ  (合作)
影响因子:2.428 (2012)

  • chemical 化学的
  • treating 处理
  • ratio 
  • compounds 化合物
  • various 千变万化的
  • uptake 上风口
  • three 
  • apical 顶端的
  • major 知的
  • efflux