School-based countrywide seroprevalence survey reveals spatial heterogeneity in malaria transmission in the Gambia.
作者: Joseph OkebeMuna AffaraSimon CorreaAbdul Khalie MuhammadDavis NwakanmaChris DrakeleyUmberto D'Alessandro
刊名: PLoS ONE, 2017, Vol.9 (10)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0110926
原始语种摘要: As the geographical distribution of malaria transmission becomes progressively clustered, identifying residual pockets of transmission is important for research and for targeting interventions. Malarial antibody-based surveillance is increasingly recognised as a valuable complement to classic methods for the detection of infection foci especially at low transmission levels. The study presents serological evidence for transmission heterogeneity among school children in The Gambia measured during the dry, non-transmission season.Healthy primary school children were randomly selected from 30 schools across the country and screened for malaria infection (microscopy) and antimalarial antibodies (MSP119). Antibody distribution was modelled using 2-component finite mixture model with cut-off for...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • malaria 疟疾
  • heterogeneity 不均匀性
  • parasite 寄生物
  • transmission 传送
  • antibody 抗体
  • progressively 前进地
  • seropositivity 血清阳性
  • school 学校
  • asymptomatic 无症状的
  • component 成分