Successful in vivo hyperthermal therapy toward breast cancer by Chinese medicine shikonin-loaded thermosensitive micelle
作者: Su YHuang NChen DZhang LDong XSun YZhu XZhang FGao JWang YFan KLo PLi WLing CQ
刊名: International Journal of Nanomedicine, 2017, Vol.Volume 12 , pp.4019-4035
来源数据库: Directory of Open Access Journals
关键词: Thermosensitive micelleShikoninBreast cancerIntra-tumor accumulation
原始语种摘要: Yonghua Su,1,* Nian Huang,1,* Di Chen,2,* Li Zhang,2,* Xia Dong,2 Yun Sun,2 Xiandi Zhu,2 Fulei Zhang,2 Jie Gao,2 Ying Wang,2 Kexing Fan,2 Puichi Lo,3 Wei Li,2 Changquan Ling1 1Department of Integrative Oncology, Changhai Hospital of Traditional Chinese Medicine, 2International Joint Cancer Institute, The Second Military Medical University, Shanghai, 3Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong, China *These authors contributed equally to this work Abstract: The Chinese traditional medicine Shikonin is an ideal drug due to its multiple targets to tumor cells. But in clinics, improving its aqueous solubility and tumor accumulation is still a challenge. Herein, a copolymer with tunable poly(N-isopropylacrymaide) and polylactic acid block lengths...
全文获取路径: PDF下载  DOAJ  (合作)
影响因子:3.463 (2012)

  • micelle 胶束
  • hyperthermal 高温期
  • loaded 加负荷的
  • breast 胸部
  • resulting 引起的
  • accumulation 堆积
  • corresponding 对应的
  • heating 加热
  • medicine 
  • cancer 癌症