Metabolic syndrome and breast cancer risk: a case-cohort study nested in a multicentre italian cohort.
作者: Claudia AgnoliSara GrioniSabina SieriCarlotta SacerdoteFulvio RicceriRosario TuminoGraziella FrascaValeria PalaAmalia MattielloPaolo ChiodiniLicia IacovielloAmalia De CurtisSalvatore PanicoVittorio Krogh
刊名: PLoS ONE, 2017, Vol.10 (6)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0128891
原始语种摘要: Metabolic syndrome (defined as at least three among abdominal obesity, high blood triglycerides, low high-density lipoprotein cholesterol, high blood glucose, and high blood pressure) is emerging as a risk factor for breast cancer; however few studies - most confined to postmenopausal women - have investigated associations between breast cancer risk and metabolic syndrome. The purpose of this study was to examine the association between metabolic syndrome and its components, and risk of breast cancer in postmenopausal and premenopausal women.We performed a case-cohort study on 22,494 women recruited in 1993-1998 to four Italian centres (Turin, Varese, Naples, Ragusa) of the European Prospective Investigation into Cancer and Nutrition (EPIC) and followed-up for up to 15 years. A random...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • breast 胸部
  • premenopausal 绝经前期的
  • cohort 伙伴
  • syndrome 症候群
  • cancer 癌症
  • postmenopausal 经绝后的
  • women 妇女
  • metabolic 新陈代谢的
  • lipoprotein 脂蛋白
  • glucose 葡萄糖