Facile Synthesis of Functionalized Spiropyrrolizidine Oxindoles via a Three-Component Tandem Cycloaddition Reaction
作者: Tai-Ran KangTing-Ting YanJie LiuHong-Bao SunYong-Mei XieYu-Qin Yao
刊名: Molecules, 2011, Vol.16 (10), pp.8745-8757
来源数据库: Directory of Open Access Journals
DOI: 10.3390/molecules16108745
关键词: Spiropyrrolizidine oxindolesCycloadditionIsatin
原始语种摘要: An efficient synthesis of functionalized spiropyrrolizidine oxindoles via a three-component tandem cycloaddition has been achieved. This strategy can provide direct and rapid access to spiropyrrolizidine oxindoles in high yields (up to 99%) with excellent diastereoselectivities (up to 99:1 dr). The features of this procedure are the following: mild reaction conditions, high yields, high diastereoselectivities, one-pot procedure and operational simplicity.
全文获取路径: DOAJ  (合作)
影响因子:2.428 (2012)

  • simplicity 简单
  • procedure 手续
  • efficient 有用的
  • features 特征
  • cycloaddition 环加
  • excellent 优秀的
  • component 成分
  • operational 运算的
  • reaction 反酌
  • rapid 急流急滩