Prognostic Role of Tumor-Infiltrating Lymphocytes in Esophagus Cancer: a Meta-Analysis
作者: Xiao ZhengXing SongYingjie ShaoBin XuWenwei HuQi ZhouLujun ChenDachuan ZhangChangping WuJingting Jiang
刊名: Cellular Physiology and Biochemistry, 2018, Vol.45 (2), pp.720-732
来源数据库: Directory of Open Access Journals
DOI: 10.1159/000487164
关键词: TilsPrognosisEsophagus cancerBiomarkerMeta-analysis
原始语种摘要: Background/Aims: Several studies have verified the correlation between tumor-infiltrating lymphocytes (TILs) and survival of patients with esophagus cancer (EC). However, the prognostic role of TILs is still controversial. Therefore, we performed this meta-analysis. Methods: We searched PubMed, Embase and the Cochrane Library (last update by August 30, 2017) to identify studies assessing the effect of TILs on survival of patients with EC. Pooled hazard ratios (HRs) for overall survival (OS), disease-free survival (DFS) and cancer specific survival (CSS) were estimated using fixed-effects models or random-effects models, which depends on the heterogeneity. Results: Data from 22 observational studies including 2909 patients were summarized. Pooled analysis indicated that generalized TILs...
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关键词翻译
关键词翻译
  • survival 生存
  • prognostic 预测的
  • infiltrating 浸润的
  • esophagus 食道
  • Cancer 巨蟹座
  • favorable 好意的
  • associated 相关的
  • including 包括(气导)包括……在内包括…在内
  • analysis 分析
  • cancer 癌症