Sinapyl Alcohol Derivatives from the Lipo-soluble Part of Dichrocephala benthamii C. B. Clarke
作者: Xinhui TianZhongmei ZouHong ChenLi LiYanbao HuChaozhong PengGang Ding
刊名: Molecules, 2013, Vol.18 (2), pp.1720-1727
来源数据库: Directory of Open Access Journals
DOI: 10.3390/molecules18021720
关键词: Dichrocephala benthamii C. B. ClarkeAsteraceaeSinapyl alcohol derivativesAbsolute configuration determinationCytotoxicity
原始语种摘要: Four new sinapyl alcohol derivatives dichrocephols A–D (compounds 1–4) were isolated from the lipo-soluble part of the whole herb of Dichrocephala benthamii C. B. Clarke, together with the known compound syringenin isovalerate (5). Their structures were elucidated on the basis of spectroscopic analysis. Their absolute configurations were established by the method of alkaline hydrohysis. Compounds 1–3 showed moderate cytotoxity against HeLa cells, with IC50 values of 14.8 μM, 51.6 μM and 81.6 μM, respectively. This is the first time that sinapyl alcohol derivatives were isolated from the genus Dichrocephala.
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影响因子:2.428 (2012)

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关键词翻译
关键词翻译
  • soluble 可溶的
  • alcohol 
  • determination 测定
  • derivatives 派生物
  • configuration 配置
  • together 共同
  • isovalerate 异戊酸
  • isolated 隔离
  • genus 
  • known 己知