Altered Right Ventricular Kinetic Energy Work Density and Viscous Energy Dissipation in Patients with Pulmonary Arterial Hypertension: A Pilot Study Using 4D Flow MRI.
作者: Q Joyce HanWalter R T WitscheyChristopher M Fang-YenJeffrey S ArklesAlex J BarkerPaul R ForfiaYuchi Han
刊名: PLoS ONE, 2017, Vol.10 (9)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0138365
原始语种摘要: Right ventricular (RV) function has increasingly being recognized as an important predictor for morbidity and mortality in patients with pulmonary arterial hypertension (PAH). The increased RV after-load increase RV work in PAH. We used time-resolved 3D phase contrast MRI (4D flow MRI) to derive RV kinetic energy (KE) work density and energy loss in the pulmonary artery (PA) to better characterize RV work in PAH patients.4D flow and standard cardiac cine images were obtained in ten functional class I/II patients with PAH and nine healthy subjects. For each individual, we calculated the RV KE work density and the amount of viscous dissipation in the PA.PAH patients had alterations in flow patterns in both the RV and the PA compared to healthy subjects. PAH subjects had significantly higher...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • density 密度
  • MRI Machine-Readable Information
  • ejection 喷出
  • hypertension 高血压
  • predictor 预示
  • function 函数
  • energy 能量
  • healthy 健康的
  • characterize 成为...的特性
  • viscous 粘滞的