Association of cytokines, neurological disability, and disease duration in HAM/TSP patients Associação de citocinas, incapacidade neurológica e duração da doença em pacientes com mielopatia associada ao HTLV-I/paraparesia espástica tropical (MAH/PET)
作者: André Luiz MunizWaldyr Rodrigues Jr.Silvane B. SantosAmélia R. de JesusAurélia F. PortoNéviton CastroJamary Oliveira-FilhoJuliana Passos AlmeidaOtávio Moreno-CarvalhoEdgar M. Carvalho
刊名: Arquivos de Neuro-Psiquiatria, 2006, Vol.64 (2a), pp.217-221
来源数据库: Directory of Open Access Journals
DOI: 10.1590/S0004-282X2006000200009
关键词: Vírus 1 linfotrópico T humanoDoenças do sistema nervosoCitocinasIncapacidade neurológicaHuman T-lymphotropic virus 1Nervous system diseasesCytokinesNeurological disability
原始语种摘要: OBJECTIVE: To identify clinical and immunological markers associated with HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP). METHOD: 237 HTLV-I infected individuals were clinically assessed. They were classified according to the Expanded Disability Status Scale (EDSS) and Osame’s Motor Disability Score (OMDS). Cytokine levels were determined in HTLV-I seropositive individuals. RESULTS: 37 patients had HAM/TSP. There was a correlation between the degrees of disability assessed by both scales. There was also a correlation between the duration of HAM/TSP and the severity of disability assessed by either EDSS or OMDS. Higher levels of IFN-gamma were detected in unstimulated peripheral blood mononuclear cells (PBMC) from HAM/TSP patients as compared with HTLV-I carriers....
全文获取路径: DOAJ  (合作)
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影响因子:0.827 (2012)

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关键词翻译
关键词翻译
  • disability 回弹率
  • foram 有孔虫
  • TSP Temporary Storage Program
  • cytokines 细胞浆移动
  • myelopathy 脊髓病
  • duration 持续时间
  • seropositive 血清反应阳性的
  • gamma 伽马
  • mononuclear 单核的
  • immunological 免疫学的