Experimental Approach to Evaluate the 11C Perfusion and Diffusion in Small Animal Tissues for HadronPET Applications.
作者: Immaculada Martínez-RoviraRaphaël BoisgardGéraldine PottierBertrand KuhnastSébastien Jan
刊名: PLoS ONE, 2017, Vol.11 (3)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0151212
原始语种摘要: The development of a reliable dose monitoring system in hadron therapy is essential in order to control the treatment plan delivery. Positron Emission Tomography (PET) is the only method used in clinics nowadays for quality assurance. However, the accuracy of this method is limited by the loss of signal due to the biological washout processes. Up to the moment, very few studies measured the washout processes and there is no database of washout data as a function of the tissue and radioisotope. One of the main difficulties is related to the complexity of such measurements, along with the limited time slots available in hadron therapy facilities. Thus, in this work, we proposed an alternative in vivo methodology for the measurement and modeling of the biological washout parameters without...
全文获取路径: DOAJ  (合作)
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影响因子:3.73 (2012)

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关键词翻译
关键词翻译
  • washout 冲蚀
  • preclinical 临证前期的
  • radioisotope 放射性同位素
  • rodents 啮齿类
  • hadron 强子
  • methodology 方法学
  • measurement 测量
  • essential 本质的
  • database 资料库
  • PET PagE frame Table