Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: a multivariate analysis of 214 cases
作者: Maria A. PizzichettaDaniela MassiMario MandalàPaola QueiroloIgnazio StanganelliVincenzo De GiorgiGiovanni GhigliottiStefano CavicchiniPietro QuaglinoMaria T. CorradinPietro RubegniMauro AlaibacStefano AstorinoFabrizio AyalaSerena MagiLaura MazzoniMaria Ausilia ManganoniRenato TalaminiDiego SerrainoGiuseppe Palmierion behalf of the Italian Melanoma Intergroup (IMI)
作者单位: 1ivision of Oncology B, CRO Aviano National Cancer Institute
2Division of Pathological Anatomy, Department of Surgery and Translational Medicine, University of Florence
3Unit of Medical Oncology, Papa Giovanni XXIII Hospital
4Department of Medical Oncology, National Institute for Cancer Research, IRCCS San Martino
5Skin Cancer Unit, Istituto Tumori Romagna (IRST)
6Department of Dermatology, University of Florence
7Clinic of Dermatology, IRCCS San Martino-IST
8Department of Dermatology, Fondazione Ospedale Ma
刊名: Journal of Translational Medicine, 2017, Vol.15 (1), pp.1-7
来源数据库: Directory of Open Access Journals
DOI: 10.1186/s12967-017-1332-3
关键词: Nodular melanomaSuperficial spreading melanomaPrognostic indicatorsRecurrence
原始语种摘要: Abstract Background Nodular melanoma (NM) accounts for most thick melanomas and because of their frequent association with ulceration, fast growth rate and high mitotic rate, contribute substantially to melanoma-related mortality. In a multicentric series of 214 primary melanomas including 96 NM and 118 superficial spreading melanoma (SSM), histopathological features were examined with the aim to identify clinicopathological predictors of recurrence. Methods All consecutive cases of histopathologically diagnosed primary invasive SSM and NM during the period 2005–2010, were retrieved from the 12 participating Italian Melanoma Intergroup (IMI) centers. Each center provided clinico-pathological data such as gender, age at diagnosis, anatomical site, histopathological conventional parameters,...
全文获取路径: DOAJ  (合作)
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影响因子:3.459 (2012)

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关键词翻译
关键词翻译
  • melanoma 黑瘤
  • recurrence 循环
  • superficial 表面的
  • mitoses 有丝分裂
  • nodular 结核状的
  • mitotic 有丝分裂的
  • spreading 扩张
  • multivariate 多元
  • significantly 较大地
  • sentinel 标志