Effects of chitosan on intestinal inflammation in weaned pigs challenged by enterotoxigenic Escherichia coli.
作者: Dingfu XiaoYongfei WangGang LiuJianhua HeWei QiuXionggui HuZemeng FengMaoliang RanCharles M NyachotiSung Woo KimZhiru TangYulong Yin
刊名: PLoS ONE, 2017, Vol.9 (8)
来源数据库: Directory of Open Access Journals
DOI: 10.1371/journal.pone.0104192
原始语种摘要: The aim of this study was to investigate whether supplementation with chitosan (COS) could reduce diarrhea and to explore how COS alleviates intestinal inflammation in weaned pigs. Thirty pigs (Duroc×Landrace×Yorkshire, initial BW of 5.65±0.27) weaned at age 21 d were challenged with enterotoxigenic Escherichia coli during a preliminary trial period, and then divided into three treatment groups. Pigs in individual pens were fed a corn-soybean meal diet, that contained either 0 (control), 50 mg/kg chlortetracycline, or 300 mg/kg COS for 21 days. The post-weaning diarrhea frequency, calprotectin levels and TLR4 protein expression were decreased (P<0.05) in both the COS and chlortetracycline groups compared with control. Simultaneously, supplemental COS and chlortetracycline had no effect on...
全文获取路径: DOAJ  (合作)
影响因子:3.73 (2012)

  • inflammation 炎症
  • chitosan 壳聚糖
  • weaning 断奶
  • jejunal 空肠的
  • intestinal 肠的
  • investigate 
  • supplemental 补充的
  • expression 表示
  • whether 是否
  • mucosa 粘膜