Susceptibility of prediabetes to the health effect of air pollution: a community-based panel study with a nested case-control design
作者: Yiqun HanYanwen WangWeiju LiXi ChenTao XueWu ChenYunfei FanXinghua QiuTong Zhu
刊名: Environmental Health, 2019, Vol.18 (1), pp.1-9
来源数据库: Directory of Open Access Journals
DOI: 10.1186/s12940-019-0502-6
关键词: PM2.5PrediabetesSusceptibilityCardiometabolic biomarkersPanel study
原始语种摘要: Abstract Background Recent studies suggest that people with diabetes or who are at risk of developing diabetes, i.e. prediabetic (preDM), are potentially susceptible to air pollution, but the underlying mechanisms remain unclear because the existing epidemiological studies did not include healthy control groups and only focused on limited health outcomes. We hypothesized that acute exposure to ambient fine particles (PM2.5) will lead to enhanced pulmonary and cardiometabolic changes in preDM than healthy individuals. Methods We recruited 60 preDM and 60 healthy individuals from a community of 22,343 adults in Beijing China, and arranged each subject to complete up to seven repeated clinical visits with measures of 6 cardiopulmonary biomarkers, 6 cytokines, 4 blood pressure and endothelial...
全文获取路径: DOAJ  (合作)
影响因子:2.714 (2012)

  • prediabetes 前驱糖尿病
  • effect 效应
  • community 群落
  • interleukin 白细胞间介素
  • pollution 污染
  • glucose 葡萄糖
  • preceding 上述的
  • acute 急尖的
  • exposure 暴露
  • elevation 隆起