Role of Different Pre-Treatments on Composition and Rheology of Synovial Fluids
作者: Marguerite RinaudoYves RozandPierre MathieuThierry Conrozier
刊名: Polymers, 2009, Vol.1 (1), pp.16
来源数据库: Directory of Open Access Journals
关键词: hyaluronansteric exclusion chromatographyrheologycentrifugationfreezingfiltrationprotease treatment
原始语种摘要: Different pre-treatments applied to synovial fluids (SF) before their analyses are tested to characterize SF after storage under different conditions and to investigate their evolution along a viscosupplementation treatment. The main techniques proposed involve steric exclusion chromatography with triple detection (SEC) and viscometry; it is the first time that such a study is developed. SEC gives the molecular weight distribution and concentration of hyaluronan (HA) and proteins separately; the steady state viscosity is always non-Newtonian and not directly related to SF composition. Pre-treatment of SF (storage in cold, filtration, centrifugation) allows us to conclude that, in order to store SF, it is best to freeze it, even if in some cases, viscosity is modified but not the...
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  • treatment 处理
  • filtration 过滤
  • their 他们的
  • conditions 条件式
  • centrifugation 离心分离
  • conclude 结论
  • separately 个别的
  • applied 应用的
  • viscometry 粘度测定法
  • modified 改进