Comparison of prevalence, viral load, physical status and expression of human papillomavirus-16, -18 and -58 in esophageal and cervical cancer: a case-control study
作者: Zhang DonghongZhang QingyingZhou LiHuo LeijunZhang YiShen ZhongyingZhu Yi
刊名: BMC Cancer, 2010, Vol.10 (1), pp.650
来源数据库: Directory of Open Access Journals
原始语种摘要: Abstract Background Human papillomavirus (HPV) infection is a major risk factor for the development of nearly all cases of cervical cancer worldwide. The presence of HPV DNA in cases of esophageal squamous-cell carcinoma (ESCC) has been reported repeatedly from Shantou, China, and other regions with a high incidence of esophageal carcinoma (EC). However, unlike in cervical squamous-cell carcinoma (CSCC), in ESCC, the characteristics of HPV are unclear. Thus, the role of high-risk HPV types in the carcinogenesis of ESCC remains uncertain. Methods Seventy cases of ESCC with 60 controls and 39 cases of CSCC with 54 controls collected from patients in Shantou region in China were compared for the distributions of HPV-16, -18 and -58; viral load; and viral integration using real-time PCR assay...
全文获取路径: DOAJ  (合作)
影响因子:3.333 (2012)

  • cervical 颈的
  • and 
  • papillomavirus 乳头状瘤病毒
  • esophageal 食管的
  • carcinogenesis 癌形成
  • expression 表示
  • physical 物理的
  • squamous 具鳞的
  • carcinoma 癌症
  • integration 集成