In Vitro Antioxidant and Xanthine Oxidase Inhibitory Activities of Methanolic Swietenia mahagoni Seed Extracts
作者: Geethaa SahgalSurash RamanathanSreenivasan SasidharanMohd Nizam MordiSabariah IsmailSharif Mahsufi Mansor
刊名: Molecules, 2009, Vol.14 (11), pp.4476
来源数据库: Directory of Open Access Journals
关键词: Swietenia mahagoni seedantioxidant activityHPTLC
原始语种摘要: This study examines the in vitro antioxidant activities of the methanol extract of Swietenia mahagoni seeds (SMCM seed extract). The extract was screened for possible antioxidant activities by free radical scavenging activity (DPPH), xanthine oxidase inhibition (XOI), hydrogen peroxide scavenging activity (HPSA) and ferric-reducing antioxidant power (FRAP) assays. The total phenolic and flavonoid contents were also determined. The extract exhibits antioxidant activity of 23.29% with an IC50 value of 2.3 mg/mL in the DPPH radical scavenging method, 47.2% in the XOI assay, 49.5% by the HPSA method, and 0.728 mmol/Fe(II)g in the FRAP method at the concentration tested. The amount of total phenolics and flavonoid contents was 70.83 mg gallic acid equivalent (GAE) and 2.5 ± 0.15 mg of catechin...
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影响因子:2.428 (2012)

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关键词翻译
关键词翻译
  • scavenging 扫气
  • extract 提取
  • radical 
  • antioxidant 抗氧化剂
  • xanthine 黄质
  • flavonoid 黄酮类
  • gallic 制图布
  • phenolic 苯酚的
  • catechin 八茶酸
  • oxidase 氧化酶