HISTOLOGICAL AND HISTOCHEMICAL CHANGES IN THE LIVER OF RATS TREATED BY GENTAMICIN AND ENALAPRIL
作者: Nenad StojiljkovicDragoljub JovanovicSlavimir VeljkovicGoran RankovicVoja PavlovicDragan RadovanovicMilan Stoiljkovic
刊名: Acta Medica Medianae, 2004, Vol.43 (2), pp.19
来源数据库: Directory of Open Access Journals
关键词: liverGentamicinEnalapril
原始语种摘要: We have examined histological and histochemical changes in the liver of rats treated by Gentamicin and Enalapril.Using the experimental group of animals (10 rats) treated by Gentamicin in the dosage of 100 mg/kg BW/24h and Enalapril in the dosage 1 mg/kg/BW/24h during the period of 8 days, it was found that in all lobuluses of the liver, changes were concentrated around periportal and intermediary zones. In the cytoplasm of these hepatocytes small fatty drops were found, so that they suppressed the nucleus and the borders of cytoplasm towards the cell membrane. Simultaneously, rare acidophilic hepatocyte regeneration was present. Glycogen reduction (+) in the experimental group of rats was proportional to the distribution of the changes characterized by fatty micro-drops. In the intact...
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关键词翻译
关键词翻译
  • liver 
  • histochemical 组织化学的
  • lobular 小裂片状的
  • periportal 门静脉周的
  • indirectly 间接地
  • hepatocyte 肝细胞
  • treated 加工的
  • cytoplasm 细胞质
  • intact 完整的
  • comparative 比较的