IL TRATTAMENTO DEL CARCINOMA DEL COLON-RETTO METASTATICO OLTRE LA SECONDA LINEA: EVIDENZE NEL PAZIENTE ANZIANO
作者: G. Buccafusca S. Rametta Giuliano P. Tralongo
刊名: Argomenti di Oncologia Geriatrica, 2018, Vol.3 (2)
来源数据库: Edi Sciences
关键词: Metastatic colorectal cancerTreatment beyond the second lineEldlerlyRegorafenibTrifluridine/tipiracil
原始语种摘要: Metastatic colorectal cancer (mCRC) is the third leading cause of cancer deaths worldwide. Median overall survival (OS) of patients with metastatic colorectal cancer (mCRC) has reached up to 30 months in recent clinical trials of frst line therapies. Following disease progression after the standard in both, 1st and 2nd line, combination chemotherapy with monoclonal antibodies, many patients maintain a good performance status and a signifcant proportion is motivated to undergo further therapy. Choices of treatment beyond the second line setting for mCRC are therefore becoming increasingly important. At the same time, longer life expectancy increases the number of elderly patients with colorectal cancer (CRC) potentially in need of oncology treatment. Unfortunately, elderly patients (≥65...
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关键词翻译
关键词翻译
  • second 
  • years 年代
  • therefore 因此
  • option 选择
  • approved 认可的
  • chemotherapy 化学疗法
  • improved 改进
  • increasingly 愈加
  • elderly 上了年纪的
  • concerning 涉及