Neonatal sepsis biomarkers: where are we now?
作者: Margaret GilfillanVineet Bhandari
作者单位: 1St Christopher’s Hospital for Children, Drexel College of Medicine
2St. Christopher's Hospital for Children/Drexel University College of Medicine
刊名: Research and Reports in Neonatology, 2019, Vol.2019 (default), pp.9-20
来源数据库: Dove Journal
DOI: 10.2147/RRN.S163082
原始语种摘要: Given that neonatal sepsis remains an important factor contributing to mortality and morbidity in neonates, identification of accurate biomarkers to aid in its timely and accurate diagnosis is critical. In this review we will discuss the current evidence behind the use of biomarkers commonly used in clinical practice as well as presenting the recent developments in this area of research. Besides summarizing information regarding “traditional” biomarkers (hematological indices, CRP and other acute phase reactants, cytokines etc.), we provide the latest clinical status on some relatively “newer” biomarkers (PCR- and “omics” technology -based, biophysical biomarkers etc.) in the diagnosis of neonatal sepsis. We believe that certain biophysical (RALIS, core-peripheral temperature differences)...
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关键词翻译
关键词翻译
  • sepsis 败血症
  • promise 允诺
  • discuss 议论
  • neonatal 新生儿的
  • summarizing 求和
  • optimal 最佳的
  • decision 决定
  • likelihood 似然
  • practice 实践
  • timely 及时的