Molecular Epidemiology of Novel Pathogen “Brachyspira hampsonii” Reveals Relationships between Diverse Genetic Groups, Regions, Host Species, and Other Pathogenic and Commensal Brachyspira Species
作者: Nandita S. MirajkarAschalew Z. BekeleYogesh Y. ChanderConnie J. Gebhart
作者单位: 1aDepartment of Veterinary and Biomedical Sciences, University of Minnesota, Saint Paul, Minnesota, USA
2bDepartment of Veterinary Population Medicine, University of Minnesota, Saint Paul, Minnesota, USA
3cVeterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, Saint Paul, Minnesota, USA
刊名: Journal of Clinical Microbiology, 2015, Vol.53 (9), pp.2908-2918
来源数据库: Duke University Press
DOI: 10.1128/JCM.01236-15
原始语种摘要: Outbreaks of bloody diarrhea in swine herds in the late 2000s signaled the reemergence of an economically significant disease, swine dysentery, in the United States. Investigations confirmed the emergence of a novel spirochete in swine, provisionally designated “Brachyspira hampsonii,” with two genetically distinct clades. Although it has since been detected in swine and migratory birds in Europe and North America, little is known about its genetic diversity or its relationships with other Brachyspira species. This study characterizes B. hampsonii using a newly developed multilocus sequence typing (MLST) approach and elucidates the diversity, distribution, population structure, and genetic relationships of this pathogen from diverse epidemiological sources globally. Genetic...
全文获取路径: Duke University Press 
影响因子:4.068 (2012)

  • genetic 遗传的
  • microevolution 微进化
  • distinct 相异的
  • clustering 聚类
  • species 
  • swine 
  • confirmed 已确认的
  • relatedness 关联性
  • isolates 单离体
  • commensal 同住者