Benchtop and animal validation of a portable fluorescence microscopic imaging system for potential use in cholecystectomy
作者: Jian YeGuanghui LiuPeng LiuShiwu ZhangPengfei ShaoZachary J. SmithChenhai LiuRonald X. Xu
作者单位: 1University of Science and Technology of China
2Anhui Provincial Hospital
3Ohio State University
刊名: Journal of Biomedical Optics, 2018, Vol.23 (2), pp.020504-020504
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.2.020504
关键词: Fluorescence microscopic imagingCholecystectomyImage-guided surgeryBiliary injuries
原始语种摘要: We propose a portable fluorescence microscopic imaging system (PFMS) for intraoperative display of biliary structure and prevention of iatrogenic injuries during cholecystectomy. The system consists of a light source module, a camera module, and a Raspberry Pi computer with an LCD. Indocyanine green (ICG) is used as a fluorescent contrast agent for experimental validation of the system. Fluorescence intensities of the ICG aqueous solution at different concentration levels are acquired by our PFMS and compared with those of a commercial Xenogen IVIS system. We study the fluorescence detection depth by superposing different thicknesses of chicken breast on an ICG-loaded agar phantom. We verify the technical feasibility for identifying potential iatrogenic injury in cholecystectomy using a...
全文获取路径: SPIE  (合作)
影响因子:2.881 (2012)

  • potential 
  • imaging 图像形成
  • microscopic 微观的
  • iatrogenic 医原性的
  • fluorescence 荧光
  • portable 携带式的
  • validation 证实
  • Fluorescence 荧光
  • biliary 胆汁的
  • system