Monitoring metabolic reactions in Staphylococcus epidermidis exposed to silicon nitride using in situ time-lapse Raman spectroscopy
作者: Francesco BoschettoTetsuya AdachiSatoshi HoriguchiDanny FainozziFulvio ParmigianiElia MarinWenliang ZhuBryan J. McEntireToshiro YamamotoNarisato KanamuraOsam MazdaEriko OhgitaniGiuseppe Pezzotti
作者单位: 1Kyoto Institute of Technology
2Kyoto Prefectural University of Medicine
3University of Trieste
4Amedica Corporation
5Tokyo Medical University
6Osaka University
7The Center for Advanced Insect Research Promotion (CAIRP)
刊名: Journal of Biomedical Optics, 2018, Vol.23 (5), pp.056002-056002
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.5.056002
关键词: Silicon nitrideStaphylococcus epidermidisBacteriostatic behaviorRaman spectroscopy
原始语种摘要: Staphylococcus epidermidis ( S. epidermidis ) is one of the leading nosocomial pathogens, particularly associated with periprosthetic infections of biomedical implants. Silicon nitride (Si3N4), a nonoxide biomaterial widely used in spinal implants, has shown bacteriostatic effects against both gram-positive and gram-negative bacteria; however, the physicochemical interactions between Si3N4 and bacteria yet remain conspicuously unexplored. In situ time-lapse Raman spectroscopic experiments were conducted by exposing S. epidermidis for 12, 24, and 48 h to Si3N4 substrates to understand the evolution of bacterial metabolism and to elucidate the ceramics antimicrobial behavior. The Raman probe captured an initial metabolic...
全文获取路径: SPIE  (合作)
影响因子:2.881 (2012)

  • bacterial 细菌的
  • lysis 分解
  • biofilm 生物薄膜
  • degradation 减嚣夷酌
  • spectroscopy 分光学
  • suggested 建议
  • initial 开首字母
  • adjust 
  • peptidoglycan 肽聚糖
  • efficiency 效率