Fluorescence molecular tomography reconstruction via discrete cosine transform-based regularization
作者: Junwei ShiFei LiuJiulou ZhangJianwen LuoJing Bai
作者单位: 1Tsinghua University
刊名: Journal of Biomedical Optics, 2015, Vol.20 (5), pp.055004-055004
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.20.5.055004
关键词: fluorescence molecular tomographyinverse problemlimited projectionsregularized reconstruction algorithmdiscrete cosine transformin vivo imaging
原始语种摘要: Fluorescence molecular tomography (FMT) as a noninvasive imaging modality has been widely used for biomedical preclinical applications. However, FMT reconstruction suffers from severe ill-posedness, especially when a limited number of projections are used. In order to improve the quality of FMT reconstruction results, a discrete cosine transform (DCT) based reweighted L1-norm regularization algorithm is proposed. In each iteration of the reconstruction process, different reweighted regularization parameters are adaptively assigned according to the values of DCT coefficients to suppress the reconstruction noise. In addition, the permission region of the reconstructed fluorophores is adaptively constructed to increase the convergence speed. In order to evaluate the performance of the...
全文获取路径: SPIE 
影响因子:2.881 (2012)

  • regularization 正则化
  • reconstruction 复原
  • cosine 余弦
  • tomography 断层x 线摄影
  • phantom 受精台
  • transform 变换
  • reconstructed 修]重构[建
  • employed 就业
  • Fluorescence 荧光
  • molecular 分子的