Nonscanning large-area Raman imaging for ex vivo / in vivo skin cancer discrimination
作者: Elmar SchmälzlinBenito MoralejoIngo GersondeJohannes SchleusenerMaxim E. DarvinGisela ThiedeMartin M. Roth
作者单位: 1innoFSPEC Potsdam
2Charité—Universitätsmedizin Berlin
3University of Potsdam
刊名: Journal of Biomedical Optics, 2018, Vol.23 (10), pp.105001-105001
来源数据库: SPIE-the International Society for Optical Engineering
DOI: 10.1117/1.JBO.23.10.105001
关键词: Raman spectroscopyCancer diagnosisRaman imagingMultichannelAstronomyEpidermisDermis
原始语种摘要: Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique of integral field spectroscopy (IFS) from astronomy to Raman imaging, it becomes possible to record entire Raman images quickly within a single exposure, without the need for a tedious scanning procedure. An IFS-based Raman imaging setup is presented, which is capable of measuring skin ex vivo or in vivo . It is demonstrated how Raman images of healthy and cancerous skin biopsies were recorded and analyzed.
全文获取路径: SPIE  (合作)
影响因子:2.881 (2012)

  • imaging 图像形成
  • cancerous 癌性的
  • spectroscopy 分光学
  • routine 程序
  • IFS Interactive File-Sharing
  • astronomy 天文学
  • transferring 转录
  • tedious 乏味的
  • scanning 扫描
  • generate